The gold standard in anti-aging and acne treatment. Clinically proven to reduce fine lines, unclog pores, and improve skin texture.
Whether you have dry, sensitive skin or oily, acne-prone skin, we have the perfect Tretinoin solution for you.
Best for: Anti-Aging & Dry Skin
A rich, emollient base that helps minimize irritation while delivering potent retinoic acid to the skin. Perfect for beginners and those targeting fine lines.
Best for: Acne & Oily Skin
A lightweight, fast-absorbing gel formulation that penetrates pores deeply. Ideal for treating active acne and preventing future breakouts.
| Feature | Tretinoin Cream | Tretinoin Gel |
|---|---|---|
| Skin Type | Dry, Sensitive, Mature | Oily, Acne-Prone, Resilient |
| Texture | Thick, Creamy, White | Clear, Lightweight, Jelly |
| Absorption | Slower, sits on skin longer | Rapid, matte finish |
| Primary Goal | Anti-Aging & Wrinkles | Acne & Blackheads |
Tretinoin, also known as all-trans retinoic acid (ATRA), is a prescription-strength medication derived from Vitamin A. Unlike over-the-counter retinol, which must be converted by your skin enzymes before it becomes active, Tretinoin is already in its active form. This makes it approximately 20 times more potent than standard retinol.
It has been the gold standard in dermatology for over 50 years, originally FDA-approved for acne but later discovered to have profound anti-aging effects.
Think of Tretinoin as a "fast-forward" button for your skin cells.
Tretinoin works at a cellular level. It penetrates the skin and binds to specific nuclear receptors (RARs and RXRs). This interaction alters gene expression to:
Reduces the depth of fine lines and wrinkles by thickening the dermis.
Unclogs pores and prevents new comedones from forming.
Fades hyperpigmentation, age spots, and melasma.
Smooths rough skin for a "glass skin" appearance.
Because Tretinoin is powerful, your skin needs time to adjust. This period is often called "Retinization."
Common temporary side effects include:
Wash your face with a gentle cleanser. Pat dry completely. Wait 20 minutes to ensure skin is dry.
Apply a pea-sized amount for the entire face. Dot it on forehead, cheeks, and chin, then spread.
Wait 10-20 minutes, then apply a thick, hydrating moisturizer to combat dryness.
Only use Tretinoin at night. You MUST wear SPF 30+ every morning as skin becomes sun-sensitive.
Start Slow!
Use it once every 3 nights for the first two weeks. Gradually increase frequency as your skin tolerates it.
"Finally found a reliable source for Tretinoin cream in the UK. Delivery was faster than expected and the Tretiheal cream has completely cleared my cystic acne in 3 months."
Sarah M.
London, UK
"I switched from expensive retinol serums to the A-Ret Gel. The difference is night and day. My skin texture is smoother and the glow is real. Highly recommend."
James P.
Manchester, UK
"Great service. I was confused between gel and cream, but the guide on the site helped me choose the cream for my dry skin. No irritation so far!"
Emily R.
Edinburgh, UK
Tretinoin is a prescription-only medication in the UK. TretinoinWorlds facilitates the purchase of legitimate products for your skincare needs.
Yes, but not at the same time. Use Vitamin C in the morning to protect against free radicals, and Tretinoin at night. Using them together can cause irritation.
Acne results can be seen in 4-12 weeks. Anti-aging benefits (wrinkle reduction) typically take 6 months of consistent use to become visibly apparent.
Join thousands of UK customers transforming their skin today.